Yes! During selected parts of April, September, and October you may be able to book a one night stay on weekends. All hotels require a 2 night (some are 3 night) stay on weekends. Sunday thru Thursdays, hotels will accept single night stays unless there is a special event. The hotels, resorts & home rentals located in the downtown area book p first, as everyone wants to be near the main strip. It is best to call the central reservation center at 888-742-7829 for the most current information.